Central pontine myelinolysis
نویسنده
چکیده
Introduction Central pontine myelinolysis (CPM) in alcoholics and malnourished patients was first described by Adams, Victor and Mancall in 1959. This commonly fatal demyelinative process that involves the pons almost exclusively, is of unknown aetiology. In the majority of the published cases, CPM was associated with chronic alcoholism, malnutrition and electrolyte abnormalities, particularly hyponatraemia. Other factors implicated in this disease have included toxins, chronic debilitation, cerebral ischaemia, infection and immunological injury. Of about 175 cases published in the literature, only 4 were reported from the United Kingdom (Adams, 1962; Tomlinson, Pierides and Bradley, 1976). The first case of CPM associated with chronic alcoholism and liver cirrhosis in this country is now described.
منابع مشابه
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